Critical Care / ICU
Clinical FrameworkSTAT / Emergent
ICU Septic Shock & Vasopressor Titration
Clinical Scenario • Critical Care / ICU
Patient: James T. (54yo M)
Bed/Room: ICU Bed 4
Attending: Dr. Patel (Intensivist)
S
Situation
Immediate clinical concern & reason for calling right now
This is Nurse Amanda in Bed 4 of the Medical ICU calling Dr. Patel.
Patient James Thornton is developing refractory septic shock with mean arterial pressure dropping to 54 mmHg despite maximum Norepinephrine infusion at 0.25 mcg/kg/min.
B
Background
Relevant clinical history, admitting diagnosis, medications & baseline
54-year-old male with severe necrotizing pancreatitis intubated on Day 4.
Access: Right internal jugular triple-lumen CVC and left radial arterial line. Currently on Norepinephrine at 0.25 mcg/kg/min and receiving IV Meropenem. Full Code.
A
Assessment
Current vital signs, objective physical findings & clinical interpretation
Invasive arterial line BP: 76/44 (MAP 54 mmHg), HR 128 sinus tachycardia, CVP 6 mmHg.
Arterial blood gas drawn 15 minutes ago reveals pH 7.22, pCO2 36, pO2 88 on 60% FiO2, with repeat serum lactate rising from 2.4 to 4.8 mmol/L. Urine output is 10 mL over the past hour.
R
Recommendation / Request
Specific clinical action needed, timeframe & read-back confirmation
I recommend initiating secondary vasopressor support with Vasopressin at 0.03 units/min fixed dose, placing a repeat cardiac output / bedside echocardiogram order, and considering IV hydrocortisone 50 mg Q6H for refractory septic shock.
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